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3 Reasons Crypto Traders Face Major Liquidation Risk This September

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Written by
Nhat Hoang

17 September 2025 07:09 UTC
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  • Bitcoin derivatives Open Interest hit $220 billion in September, signaling record liquidation risk as leveraged bets surge.
  • Futures trading now outpaces spot by up to 10x, amplifying volatility ahead of major economic and Fed-driven events.
  • Both long and short positions face liquidation clusters, with BTC swings between $104,500 and $124,000 risking billions in losses.
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The latest derivatives data for Bitcoin and the broader altcoin market indicate that traders face a major liquidation risk in September 2025.

How should traders prepare for this threat? This article examines the latest data and insights from experienced market participants.

September Derivatives Market Overheats With More Than $220 Billion in Open Interest

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The first reason lies in the record-high Open Interest in September. This figure represents the total value of open positions in the market and signals potential liquidation risk at any moment.

According to data from CoinGlass, total crypto futures Open Interest surpassed $220 billion, setting a new monthly high. Short-term traders are aggressively increasing leverage, with open positions rising sharply on expectations of upcoming economic events.

Crypto Market Open Interest. Source: Coinglass
Crypto Market Open Interest. Source: Coinglass

The second reason confirms that derivatives trading now dominates spot trading.

CoinGlass data shows the trading volume ratio of Bitcoin Perpetual Futures to Spot remains elevated, with futures volumes eight to ten times higher than spot.

Bitcoin Perpetual Futures/Spot Volume Ratio. Source: Coinglass
Bitcoin Perpetual Futures/Spot Volume Ratio. Source: Coinglass

These metrics signal the possibility of record liquidations, especially as key interest rate decisions approach.

The third reason stems from unexpected volatility, even though most traders believe they already know how the Federal Reserve will decide.

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While debates continue over whether the market will trend after the FOMC meeting, analyst Crypto Bully noted on X that the FOMC outcome does not guarantee price direction. Instead, it mainly brings volatility. This volatility can trigger losses for long and short positions, leading to mass liquidations.

CoinGlass further reports that clusters of liquidation-heavy positions lie above and below Bitcoin’s current price level.

“High leverage liquidity. Both long and short high leveraged positions will be liquidated,” CoinGlass predicted.

Bitcoin’s massive derivatives exposure could trigger record liquidations across the market. The liquidation map shows that if BTC falls to $104,500 this month, the cumulative liquidation volume for long positions could exceed $10 billion.

Conversely, if BTC rises and sets a new high above $124,000, short positions could face more than $5.5 billion in losses.

Bitcoin Exchange Liquidation Map. Source: Coinglass.

BeInCrypto also highlighted several altcoins that face significant liquidation risk this week.

What can traders do to minimize losses? Analyst Luckshury explained that trading derivatives means competing directly against exchanges. Traders must therefore identify price zones likely to trigger mass liquidations and limit their position sizes accordingly.

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