Best DeSci Projects to Watch in 2025

Galeon is a French DeSci project focused on blockchain-based healthcare solutions, founded in 2016. Since its launch, Galeon has grown into a robust ecosystem trusted by over 100,000 pioneers, including a network of 17 hospitals and major partnerships, one of which with Samsung, announced on September 23, 2025.

Galeon’s mission is to make medical data and research standardized, accessible, and easy to analyze, enabling more collaborative and data-driven healthcare innovations. Key solutions and products within the ecosystem include:

• Blockchain Swarm Learning (BSL): A technology using AI that connects hospitals to facilitate decentralized medical research. This approach makes data more secure, ensures data sovereignty, and enables hospitals to share the value of data while patients also benefit from improved data sharing, unlike traditional centralized methods.
• Electronic Health Record (EHR): A digital version of traditional medical records, enabling the centralization of patient data, medical histories, treatment results, and more. Galeon’s AI-powered EHR improves the quality of decentralized medical research, fostering global improvements in hospital operations.
• GALEON Token: The native token of the Galeon ecosystem, with over 50,000 holders, used for accessing various features in the ecosystem's apps, funding, staking (coming soon), and governance. Token holders can participate in decision-making processes through voting.

VitaDAO is a DeSci project founded in 2021, representing a community-driven platform designed to fund early-stage longevity science research. Since its launch, VitaDAO has funded 24 projects, raising over $4.5 million. One of the largest funded projects is Turn Biotechnologies, which develops medicines that support the body’s natural healing processes. This project raised $1 million.

Additionally, VitaDAO is the first decentralized autonomous organization (DAO) to launch a Biotech company: Matrix Bio, focused on research in the anti-cancer field. VitaDAO utilizes the Molecule blockchain protocol, which allows researchers to document their findings and data through NFTs.

VitaDAO has a native project token, VITA, which is used for governance, allowing token holders to participate in funding research proposals. Additionally, the token is available for staking, as well as providing holders with access to and the ability to access and monetize data repositories.

Molecule is a DeSci protocol founded in 2018 with a mission to make the scientific research process easier for people. The protocol provides a decentralized environment for funding biotechnology projects and tokenizing intellectual property data. Today, Molecule represents one of the largest DeSci ecosystems, with a $170 million ecosystem market cap and $7.85 million funded for DeSci projects.

Molecule stands out with its tokenization solutions, which help researchers raise funds more easily and streamline scientific collaboration while ensuring full transparency and immutability.

• Intellectual Property Non-Fungible Tokens (IP-NFTs): provide secure, on-chain proof of IP ownership. They make ownership transparent and immutable, allowing researchers to raise funds and monetize their IP.
• IP Tokens (IPTs): represent fractional governance over IP. Holders can participate in research decisions and influence its future development.

ResearchHub is a DeSci project providing a platform for publishing, discussing, and funding scientific research in an open, decentralized environment. It was founded in 2019 by Brian Armstrong, CEO of Coinbase, and scientist Patrick Joyce. Since its launch, it has made significant progress in addressing inefficiencies in scientific research, funding $1.2 million across 16 experiments.

The platform offers an intuitive, social-network-like interface where users can publish their research, comment on, and review others’ work. Additionally, users can earn rewards in the platform’s native token (RSC). For example, $150 in RSC for high-quality peer reviews, also making ResearchHub a marketplace for scientific collaboration. Tokens can also be earned for commenting, participating in discussions, or receiving tips from other users. In addition, RSC serves as a governance token, allowing holders to participate in platform voting. This makes ResearchHub a full-featured marketplace for scientific collaboration.

AthenaDAO is a DeSci project founded in 2022, bringing together a community of researchers, funders, and advocates. It focuses on women’s health and aims to improve the research process in this field, unlocking the untapped potential of women’s health studies.

The DAO selects projects through open calls, votes on them, and provides funding via grants or IP-NFTs, with regular reporting to ensure transparency. Its early initiatives have already allocated over $250,000 in financial support.

AthenaDAO has its native token, ATH, which serves as a governance token, allowing holders to participate in the DAO and vote on research projects. Additionally, ATH features a well-structured tokenomics model with a clear distribution mechanism and a capped maximum supply.