Crypto adoption in Latin America no longer depends solely on exchanges. Neobanks are now being used as the primary gateway. These banking platforms embed crypto into everyday financial apps used for payments, savings, and transfers.
This ranking evaluates the top five LATAM neobanks based on user scale, payments volume, crypto product depth, and real-world usage as of March 2026.
The focus is not on trading volume, which most firms do not disclose, but on how effectively each platform distributes crypto to mainstream users.
| Rank | Neobank | Total Users | Active / Engaged Users | Payments Scale (Annual TPV) | Crypto Offering Depth | Core Strength |
| 1 | Nubank | 131 Million | 109 Million | Not primary focus (lending + deposits model) | 28 assets, transfers, staking, rewards | Full crypto ecosystem at massive scale |
| 2 | Mercado Pago | 78 Million (monthly users) | 78 Million monthly active users | $278 Billion | Buy, sell, stablecoin (MUSD), payments integration | Strongest real-world crypto usage |
| 3 | Inter & Co | 43 Million | 25 Million | $360 Billion | 5 major assets via regulated infrastructure | Institutional-grade financial integration |
| 4 | PicPay | 67 Million | 42.7 Million | $100 Billion | Around 15 crypto assets, trading features | High engagement consumer wallet |
| 5 | PagBank | 34 Million | 34 Million (payments-focused engagement) | $530 Billion | Indirect crypto exposure via funds and products | Largest payments infrastructure scale |
1. Nubank – Scale Meets Full Crypto Integration
Nubank leads by a wide margin. It serves 131 million users, with more than 7 million already using crypto features.
The platform supports 28 assets, alongside staking and rewards, making it the most complete crypto offering among LATAM neobanks. Crypto sits directly inside its core banking app, not as a separate product.
This combination matters. Nubank distributes crypto access at scale. Its model shows how crypto becomes a default feature in retail finance rather than a niche activity.
2. Mercado Pago — Crypto Through Payments
Mercado Pago takes a different approach. It reaches around 78 million monthly users and processes 278 billion USD in annual payment volume.
Instead of focusing on trading, it integrates crypto into daily transactions. Users can buy, sell, and increasingly interact with stablecoins like MUSD within the payments ecosystem.
This positions Mercado Pago as a utility-driven crypto platform. Its strength lies in making crypto usable, not just investable. That distinction drives real adoption across retail users who may not identify as crypto traders.
3. Inter & Co — Institutional-Grade Access
Inter & Co combines digital banking with investment infrastructure. It has 43 million users, including 25 million active users, and manages large-scale financial flows and custody.
Its crypto offering remains more conservative. The platform supports a limited number of major assets, typically around five, delivered through regulated infrastructure.
This approach prioritizes compliance and stability over breadth. Crypto functions as an extension of its investment platform rather than a high-frequency trading feature.
4. PicPay — Engagement-Driven Growth
PicPay operates at scale with 67 million users and over 42 million active users. It processes more than 100 billion USD annually in payments.
The company reintroduced crypto in 2025, now supporting around 15 assets. Its strategy focuses on engagement, targeting users already active in payments and peer-to-peer transfers.
While its crypto user base remains smaller than Nubank’s, PicPay benefits from high activity levels. This creates a strong foundation for expanding crypto adoption through existing financial behavior.
5. PagBank — Payments Giant, Limited Crypto Depth
PagBank rounds out the list with 34 million users and one of the largest payment infrastructures in the region, handling 530 billion USD in annual volume.
Its crypto exposure remains indirect. Users access digital assets primarily through investment products and funds, rather than in-app trading.
This limits adoption compared to peers. However, PagBank’s scale positions it as a potential distribution channel if it expands its crypto offering.
What This Ranking Shows
LATAM neobanks are not competing on trading volume. They compete on distribution, accessibility, and integration into daily finance.
Nubank demonstrates how scale drives adoption. Mercado Pago shows how payments create utility. Others position crypto as either an investment layer or an engagement tool.
Together, they reflect a broader shift. Crypto adoption in Latin America increasingly happens inside banking apps people already use, not on standalone exchanges.
